1. Periodontal disease and systemic disease
2. Risk Factors for Periodontal Disease
3. Clinical History and Laboratory Tests
4. Role of Genetics in Assessment, Risk, and Management of Adult Periodontitis
5. Clinical History and Laboratory Tests
6. Relationships between Periodontal and Respiratory Diseases
1. Periodontal disease and systemic disease
oral microbial – “biofilm” – mucosal immunity ,
oral infection associate กับ systemic disease ,
commensal bacterial บน surface of teeth , prosthetic implant เรียกว่าbiofilm , บน mucosal epithelial ซึ่ง line – oral cavity , respiratory tract , GI , KUB
– microorganism เป็น oppotunistic and associate กับ local systemic infection eg Hemophilus influenza , Streptococcus pneumonia , Neisseria meningitis and Staphylococcus aureus
– ใน oral cavity มี bacterial 6 billion microbes , 300-500 species , ecosystem เป็น dynamic
– ระหว่าง human development , virus , bacterial , yeast จะ transmitted จาก แม่สู่ลูก , caretaker to child , หรือคู่สมรส spouse
gr +ve eg strptococcus sanguis , streptococcus oralis ใน infective endocarditis
มี case arthritis หลังจาก infected teetch extracted
asso oral infection eg viral ,bacterial ,yeast กับ systemiic disease eg atherosclerosis , cardio vascular , cerebrovascular , prematurity and low birth weight , pulm disease
– หรือกับ arthrtis , DM , HIV , osteoporosis ,
oral infection, bacteria – release toxin -> เกิด localized tiss response cytokine , -> systemic response
subsequent pathogenesis of disease – reflect ถึง gene-gene , gene-env
p 12 Anatomic primer of peridontium
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2. Risk Factors for Periodontal Disease
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3. Clinical History and Laboratory Tests
4. Role of Genetics in Assessment, Risk, and Management of Adult Periodontitis
5. Clinical History and Laboratory Tests
6. Relationships between Periodontal and Respiratory Diseases