Section I: Introduction
1. Magnitude and impact of osteoporosis and fractures
2. Impact of osteoporosis on quality of life and quality of life on
osteoporosis: rationale and methodology for accurate assessment
Section II: Gonadal steroids and the pathogenesis of osteoporosis

Section I: Introduction
1. Magnitude and impact of osteoporosis and fractures

bone stength – primary reflex ถึง bone quality and bone density
bone quality – architecture , turnover damage accumulation and mineralization
bone density – grams of mineral per area/volume
hip fracture จาก age-related reduction bone mass and quality
osteomalacia – bone present ลด quantity , with normal mineralization

2. Impact of osteoporosis on quality of life and quality of life on osteoporosis: rationale and methodology for accurate assessment

Section II: Gonadal steroids and the pathogenesis of osteoporosis