1: Historical Aspects
Part I Basic Features
2: Genetics and Individual Predispositions in Contact Dermatitis
3: Mechanisms of Irritant and Allergic Contact Dermatitis
4: Molecular Aspects in Allergic and Irritant Contact Dermatitis
5: Bio-Guided Fractionation and Identification of Allergens in Complex Mixtures and Products
6: Role of the Permeability Barrier in Contact Dermatitis
7: Immediate Contact Reactions
8: Mechanisms of Phototoxic and Photoallergic Reactions
Part II Pathology
9: Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis
10: Ultrastructure of Irritant and Allergic Contact Dermatitis
11: Epidemiology
Part III Dermatotoxicology
12: Skin Penetration
1: Historical Aspects
p 12 , ศต 1 Pliny พบว่าเคสคันมาก หลังไปตัด pine tree
patch testingเป็น unmask causative chemical
– open test , semi-open test , repeated open application test (ROAT) – use test
Prick testing ถือว่า underestimate – inv tool สำหรับ immediate contact hypersensitivity
p 13. 1.2 Historical Aspects of Patch Testing
2: Genetics and Individual Predispositions in Contact Dermatitis
3: Mechanisms of Irritant and Allergic Contact Dermatitis
4: Molecular Aspects in Allergic and Irritant Contact Dermatitis
5: Bio-Guided Fractionation and Identification of Allergens in Complex Mixtures and Products
6: Role of the Permeability Barrier in Contact Dermatitis
7: Immediate Contact Reactions
8: Mechanisms of Phototoxic and Photoallergic Reactions